Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia()

Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from a loss of VEGF-A-mediated neuroprotection. The multiple vegf...

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Autors principals: Hulse, R.P., Beazley-Long, N., Hua, J., Kennedy, H., Prager, J., Bevan, H., Qiu, Y., Fernandes, E.S., Gammons, M.V., Ballmer-Hofer, K., Gittenberger de Groot, A.C., Churchill, A.J., Harper, S.J., Brain, S.D., Bates, D.O., Donaldson, L.F.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194316/
https://ncbi.nlm.nih.gov/pubmed/25151644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.08.012
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