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Pharmacology of Modulators of Alternative Splicing

More than 95% of genes in the human genome are alternatively spliced to form multiple transcripts, often encoding proteins with differing or opposing function. The control of alternative splicing is now being elucidated, and with this comes the opportunity to develop modulators of alternative splici...

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Detalhes bibliográficos
Publicado no:Pharmacol Rev
Main Authors: Bates, David O., Morris, Jonathan C., Oltean, Sebastian, Donaldson, Lucy F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226212/
https://ncbi.nlm.nih.gov/pubmed/28034912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.115.011239
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