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NON-ENZYMATIC GLYCATION INTERFERES WITH FIBRONECTIN-INTEGRIN INTERACTIONS IN VASCULAR SMOOTH MUSCLE CELLS

OBJECTIVE: We aimed to investigate whether advanced non-enzymatic glycation of the extracellular matrix (ECM) protein, fibronectin, impacts its normal integrin-mediated interaction with arteriolar vascular smooth muscle cells (VSMC). METHODS: Atomic force microscopy (AFM) was performed on cultured V...

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Détails bibliographiques
Publié dans:Microcirculation
Auteurs principaux: Dhar, Srijita, Sun, Zhe, Meininger, Gerald A., Hill, Michael A.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404995/
https://ncbi.nlm.nih.gov/pubmed/28005306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12347
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