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Mechanotransduction through fibronectin-integrin focal adhesion in microvascular smooth muscle cells: is calcium essential?

It is believed that increased transmural pressure exerts force on vascular smooth muscle cells (VSMCs) and triggers Ca(2+) signaling as an initiating event responsible for the arteriolar myogenic response. However, the mechanisms linking the pressure increase to Ca(2+) signaling are unclear. We have...

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Detalhes bibliográficos
Main Authors: Sun, Zhe, Li, Zhaohui, Meininger, Gerald A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362112/
https://ncbi.nlm.nih.gov/pubmed/22427509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00598.2011
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