Lysophosphatidic acid induces integrin activation in vascular smooth muscle and alters arteriolar myogenic vasoconstriction

In vascular smooth muscle cells (VSMC) increased integrin adhesion to extracellular matrix (ECM) proteins, as well as the production of reactive oxygen species (ROS) are strongly stimulated by lysophosphatidic acid (LPA). We hypothesized that LPA-induced generation of ROS increases integrin adhesion...

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Bibliografske podrobnosti
Main Authors: Staiculescu, Marius C., Ramirez-Perez, Francisco I., Castorena-Gonzalez, Jorge A., Hong, Zhongkui, Sun, Zhe, Meininger, Gerald A., Martinez-Lemus, Luis A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215695/
https://ncbi.nlm.nih.gov/pubmed/25400583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00413
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