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Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Noridomi, Kaori, Watanabe, Go, Hansen, Melissa N, Han, Gye Won, Chen, Lin
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404922/
https://ncbi.nlm.nih.gov/pubmed/28440223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23043
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