Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...

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Udgivet i:eLife
Main Authors: Noridomi, Kaori, Watanabe, Go, Hansen, Melissa N, Han, Gye Won, Chen, Lin
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Biophysics and Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404922/
https://ncbi.nlm.nih.gov/pubmed/28440223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23043
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