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Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications

The nicotinic acetylcholine receptor (nAChR) is a major target of autoantibodies in myasthenia gravis (MG), an autoimmune disease that causes neuromuscular transmission dysfunction. Despite decades of research, the molecular mechanisms underlying MG have not been fully elucidated. Here, we present t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Noridomi, Kaori, Watanabe, Go, Hansen, Melissa N, Han, Gye Won, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404922/
https://ncbi.nlm.nih.gov/pubmed/28440223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23043
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