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The basis of sharp spike onset in standard biophysical models
In most vertebrate neurons, spikes initiate in the axonal initial segment (AIS). When recorded in the soma, they have a surprisingly sharp onset, as if sodium (Na) channels opened abruptly. The main view stipulates that spikes initiate in a conventional manner at the distal end of the AIS, then prog...
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| Published in: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5404793/ https://ncbi.nlm.nih.gov/pubmed/28441389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175362 |
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