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Sharpness of Spike Initiation in Neurons Explained by Compartmentalization

In cortical neurons, spikes are initiated in the axon initial segment. Seen at the soma, they appear surprisingly sharp. A standard explanation is that the current coming from the axon becomes sharp as the spike is actively backpropagated to the soma. However, sharp initiation of spikes is also seen...

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Autor principal: Brette, Romain
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854010/
https://ncbi.nlm.nih.gov/pubmed/24339755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003338
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