In Vivo Pharmacokinetic and Pharmacodynamic Profiles of Antofloxacin against Klebsiella pneumoniae in a Neutropenic Murine Lung Infection Model

Antofloxacin is a novel broad-spectrum fluoroquinolone under development for the treatment of infections caused by a diverse group of bacterial species. We explored the pharmacodynamic (PD) profile and targets of antofloxacin against seven Klebsiella pneumoniae isolates by using a neutropenic murine...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Zhou, Yu-Feng, Tao, Meng-Ting, Huo, Wei, Liao, Xiao-Ping, Sun, Jian, Liu, Ya-Hong
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Clinical Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404557/
https://ncbi.nlm.nih.gov/pubmed/28264844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02691-16
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