Oligonucleotide-Lipid Conjugates Forming G-Quadruplex Structures Are Potent and Pangenotypic Hepatitis C Virus Entry Inhibitors In Vitro and Ex Vivo

A hepatitis C virus (HCV) epidemic affecting HIV-infected men who have sex with men (MSM) is expanding worldwide. In spite of the improved cure rates obtained with the new direct-acting antiviral drug (DAA) combinations, the high rate of reinfection within this population calls urgently for novel pr...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Koutsoudakis, George, Paris de León, Alexia, Herrera, Carolina, Dorner, Marcus, Pérez-Vilaró, Gemma, Lyonnais, Sébastien, Grijalvo, Santiago, Eritja, Ramon, Meyerhans, Andreas, Mirambeau, Gilles, Díez, Juana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404530/
https://ncbi.nlm.nih.gov/pubmed/28193659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02354-16
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