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Synthesis of Oligonucleotides Carrying Thiol Groups Using a Simple Reagent Derived from Threoninol

Oligonucleotides carrying thiol groups are useful intermediates for a remarkable number of applications involving nucleic acids. In this study, DNA oligonucleotides carrying tert-butylsulfanyl (t-BuS) protected thiol groups have been prepared. A building block derived from threoninol has been develo...

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Bibliographic Details
Published in:Molecules
Main Authors: Pérez-Rentero, Sonia, Grijalvo, Santiago, Ferreira, Rubén, Eritja, Ramon
Format: Artigo
Language:Inglês
Published: MDPI 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268497/
https://ncbi.nlm.nih.gov/pubmed/22922274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules170910026
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