Down-regulation of E protein activity augments an ILC2 differentiation program in the thymus

Innate lymphoid cells (ILCs) are important regulators in various immune responses. Current paradigm states that all newly-made ILCs originate from common lymphoid progenitors (CLP) in the bone marrow. Id2, an inhibitor of E protein transcription factors, is indispensable for ILC differentiation. Une...

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Pubblicato in:J Immunol
Autori principali: Wang, Hong-Cheng, Qian, Liangyue, Zhao, Ying, Mengarreli, Joni, Adrianto, Indra, Montgomery, Courtney G., Urban, Joseph F., Fung, Kar-Ming, Sun, Xiao-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404348/
https://ncbi.nlm.nih.gov/pubmed/28258196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602009
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