Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors

Current models propose that group 2 innate lymphoid cells (ILC2s) are generated in the bone marrow. Here, we demonstrate that subsets of these cells can differentiate from multipotent progenitors and committed T cell precursors in the thymus, both in vivo and in vitro. These thymic ILC2s exit the th...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Qian, Liangyue, Bajana, Sandra, Georgescu, Constantin, Peng, Vincent, Wang, Hong-Cheng, Adrianto, Indra, Colonna, Marco, Alberola-Ila, Jose, Wren, Jonathan D., Sun, Xiao-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446881/
https://ncbi.nlm.nih.gov/pubmed/30898894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182100
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