LPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytes

C/EBPε is a critical transcriptional factor for granulocyte differentiation and function. Individuals with germline mutations of C/EBPε fail to develop normal granulocytes and suffer from repeated infections. In order to gain a global view of the transcriptional machinery regulated by C/EBPε, we per...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Suh, Hyung C., Benoukraf, Touati, Shyamsunder, Pavithra, Yin, Tong, Cao, Qi, Said, Jonathan, Lee, Stephen, Lim, Ricky, Yang, Henry, Salotti, Jacqueline, Johnson, Peter F., Madan, Vikas, Koeffler, H. Phillip
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404328/
https://ncbi.nlm.nih.gov/pubmed/28440307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46440
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