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Orally administered simvastatin partially preserves lumbar vertebral bone mass but not integrity of intervertebral discs in ovariectomized rats

The present study aimed to investigate the effect of orally administered simvastatin on lumbar vertebral bone mass and intervertebral disc (IVD) degeneration in ovariectomized (OVX) rats. A total of 30 female Sprague-Dawley (SD) rats were subjected to either bilateral ovariectomy (n=20) or sham surg...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Tian, Fa-Ming, Li, Shu-Yang, Yang, Kai, Luo, Yang, Dai, Mu-Wei, Liu, Guang-Yuan, Song, Hui-Ping, Zhang, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403518/
https://ncbi.nlm.nih.gov/pubmed/28450913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4043
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