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Variations in the multimerization region of the Helicobacter pylori cytotoxin CagA affect virulence

Helicobacter pylori colonizes the human stomach by infecting gastric epithelial cells. It is the primary cause of peptic ulcer disease and gastric cancer (GC). Cytotoxin-associated gene A (CagA) is a virulence factor produced by H. pylori. Strains positive for the CagA protein are associated with mo...

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Bibliografische gegevens
Gepubliceerd in:Oncol Lett
Hoofdauteurs: Ahire, Daiva, Alston, Tricia, Raffaniello, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403285/
https://ncbi.nlm.nih.gov/pubmed/28454275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5562
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