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Variations in the multimerization region of the Helicobacter pylori cytotoxin CagA affect virulence

Helicobacter pylori colonizes the human stomach by infecting gastric epithelial cells. It is the primary cause of peptic ulcer disease and gastric cancer (GC). Cytotoxin-associated gene A (CagA) is a virulence factor produced by H. pylori. Strains positive for the CagA protein are associated with mo...

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Библиографические подробности
Опубликовано в: :Oncol Lett
Главные авторы: Ahire, Daiva, Alston, Tricia, Raffaniello, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403285/
https://ncbi.nlm.nih.gov/pubmed/28454275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5562
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