Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease.

The pathogenic role of Helicobacter pylori virulence factors has been studied with a mouse model of gastric disease. BALB/c mice were treated orally with different amounts of sonic extracts of cytotoxic H. pylori strains (NCTC 11637, 60190, 84-183, and 87A300 [CagA+/Tox+]). The pathological effects...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Ghiara, P, Marchetti, M, Blaser, M J, Tummuru, M K, Cover, T L, Segal, E D, Tompkins, L S, Rappuoli, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7558333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.10.4154-4160.1995
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