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Variations in the multimerization region of the Helicobacter pylori cytotoxin CagA affect virulence

Helicobacter pylori colonizes the human stomach by infecting gastric epithelial cells. It is the primary cause of peptic ulcer disease and gastric cancer (GC). Cytotoxin-associated gene A (CagA) is a virulence factor produced by H. pylori. Strains positive for the CagA protein are associated with mo...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Ahire, Daiva, Alston, Tricia, Raffaniello, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403285/
https://ncbi.nlm.nih.gov/pubmed/28454275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5562
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