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Variations in the multimerization region of the Helicobacter pylori cytotoxin CagA affect virulence

Helicobacter pylori colonizes the human stomach by infecting gastric epithelial cells. It is the primary cause of peptic ulcer disease and gastric cancer (GC). Cytotoxin-associated gene A (CagA) is a virulence factor produced by H. pylori. Strains positive for the CagA protein are associated with mo...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Ahire, Daiva, Alston, Tricia, Raffaniello, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403285/
https://ncbi.nlm.nih.gov/pubmed/28454275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5562
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