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The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair
The protein product of the breast and ovarian cancer gene, BRCA1, is part of an obligate heterodimer with BARD1. Together these RING bearing proteins act as an E3 ubiquitin ligase. Several functions have been attributed to BRCA1 that contribute to genome integrity but which of these, if any, require...
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| 發表在: | Nucleus |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403137/ https://ncbi.nlm.nih.gov/pubmed/28032817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1267092 |
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