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Primidone inhibits TRPM3 and attenuates thermal nociception in vivo
The melastatin-related transient receptor potential (TRP) channel TRPM3 is a nonselective cation channel expressed in nociceptive neurons and activated by heat. Because TRPM3-deficient mice show inflammatory thermal hyperalgesia, pharmacological inhibition of TRPM3 may exert antinociceptive properti...
Tallennettuna:
| Julkaisussa: | Pain |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Wolters Kluwer
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402713/ https://ncbi.nlm.nih.gov/pubmed/28106668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000846 |
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