The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators

During the molecular transduction of itch, the stimulation of pruriceptors on sensory fibers leads to the activation or sensitization of ion channels, which results in a consequent depolarization of the neurons. These ion channels mostly belong to the transient receptor potential (TRP) channels, whi...

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Bibliografske podrobnosti
izdano v:Biochem Pharmacol
Main Authors: Kelemen, Balázs, Pinto, Silvia, Kim, Nawoo, Lisztes, Erika, Hanyicska, Martin, Vládar, Anita, Oláh, Attila, Pénzes, Zsófia, Shu, Brian, Vriens, Joris, Bíró, Tamás, Rohács, Tibor, Voets, Thomas, Tóth, Balázs István
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086171/
https://ncbi.nlm.nih.gov/pubmed/33130130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114310
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