The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators

During the molecular transduction of itch, the stimulation of pruriceptors on sensory fibers leads to the activation or sensitization of ion channels, which results in a consequent depolarization of the neurons. These ion channels mostly belong to the transient receptor potential (TRP) channels, whi...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Kelemen, Balázs, Pinto, Silvia, Kim, Nawoo, Lisztes, Erika, Hanyicska, Martin, Vládar, Anita, Oláh, Attila, Pénzes, Zsófia, Shu, Brian, Vriens, Joris, Bíró, Tamás, Rohács, Tibor, Voets, Thomas, Tóth, Balázs István
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086171/
https://ncbi.nlm.nih.gov/pubmed/33130130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2020.114310
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