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Primidone inhibits TRPM3 and attenuates thermal nociception in vivo
The melastatin-related transient receptor potential (TRP) channel TRPM3 is a nonselective cation channel expressed in nociceptive neurons and activated by heat. Because TRPM3-deficient mice show inflammatory thermal hyperalgesia, pharmacological inhibition of TRPM3 may exert antinociceptive properti...
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| Publicado no: | Pain |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402713/ https://ncbi.nlm.nih.gov/pubmed/28106668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000846 |
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