Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

Sensing and reacting to tissue damage is a fundamental function of immune systems. Macrophage inducible C-type lectin (Mincle) is an activating C-type lectin receptor that senses damaged cells. Notably, Mincle also recognizes glycolipid ligands on pathogens. To elucidate endogenous glycolipids ligan...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Nagata, Masahiro, Izumi, Yoshihiro, Ishikawa, Eri, Kiyotake, Ryoko, Doi, Rieko, Iwai, Satoru, Omahdi, Zakaria, Yamaji, Toshiyuki, Miyamoto, Tomofumi, Bamba, Takeshi, Yamasaki, Sho
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402399/
https://ncbi.nlm.nih.gov/pubmed/28373578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618133114
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items