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Drug-enhanced carbon monoxide production from heme by cytochrome P450 reductase
Carbon monoxide (CO) formed endogenously is considered to be cytoprotective, and the vast majority of CO formation is attributed to the degradation of heme by heme oxygenases-1 and -2 (HO-1, HO-2). Previously, we observed that brain microsomes containing HO-2 produced many-fold more CO in the presen...
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| Veröffentlicht in: | Med Gas Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Medknow Publications & Media Pvt Ltd
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402345/ https://ncbi.nlm.nih.gov/pubmed/28480030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-9912.202908 |
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