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Drug-enhanced carbon monoxide production from heme by cytochrome P450 reductase

Carbon monoxide (CO) formed endogenously is considered to be cytoprotective, and the vast majority of CO formation is attributed to the degradation of heme by heme oxygenases-1 and -2 (HO-1, HO-2). Previously, we observed that brain microsomes containing HO-2 produced many-fold more CO in the presen...

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Publicat a:Med Gas Res
Autors principals: Vukomanovic, Dragic, Rahman, Mona N., Jia, Zongchao, Nakatsu, Kanji
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402345/
https://ncbi.nlm.nih.gov/pubmed/28480030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-9912.202908
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