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A Novel, “Double-Clamp” Binding Mode for Human Heme Oxygenase-1 Inhibition
The development of heme oxygenase (HO) inhibitors is critical in dissecting and understanding the HO system and for potential therapeutic applications. We have established a program to design and optimize HO inhibitors using structure-activity relationships in conjunction with X-ray crystallographic...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261875/ https://ncbi.nlm.nih.gov/pubmed/22276118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029514 |
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