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Altered nuclear dynamics in MDX myofibers

Duchenne muscular dystrophy (DMD) is a genetic disorder in which the absence of dystrophin leads to progressive muscle degeneration and weakness. Although the genetic basis is known, the pathophysiology of dystrophic skeletal muscle remains unclear. We examined nuclear movement in wild-type (WT) and...

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Publicat a:J Appl Physiol (1985)
Autors principals: Iyer, Shama R., Shah, Sameer B., Valencia, Ana P., Schneider, Martin F., Hernández-Ochoa, Erick O., Stains, Joseph P., Blemker, Silvia S., Lovering, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401960/
https://ncbi.nlm.nih.gov/pubmed/27979987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00857.2016
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