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Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Iyer, Shama, Ward, Christopher, Stains, Joseph, Ryan, Alice, Folker, Eric, Lovering, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742940/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.424
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