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Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and...

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Bibliografiska uppgifter
I publikationen:Innov Aging
Huvudupphovsmän: Iyer, Shama, Ward, Christopher, Stains, Joseph, Ryan, Alice, Folker, Eric, Lovering, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742940/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.424
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