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Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and...

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Bibliografische gegevens
Gepubliceerd in:Innov Aging
Hoofdauteurs: Iyer, Shama, Ward, Christopher, Stains, Joseph, Ryan, Alice, Folker, Eric, Lovering, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742940/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.424
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