Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and...

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Bibliografske podrobnosti
izdano v:Innov Aging
Main Authors: Iyer, Shama, Ward, Christopher, Stains, Joseph, Ryan, Alice, Folker, Eric, Lovering, Richard
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742940/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.424
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