Altered nuclear dynamics in MDX myofibers

Duchenne muscular dystrophy (DMD) is a genetic disorder in which the absence of dystrophin leads to progressive muscle degeneration and weakness. Although the genetic basis is known, the pathophysiology of dystrophic skeletal muscle remains unclear. We examined nuclear movement in wild-type (WT) and...

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Publicado en:J Appl Physiol (1985)
Autores principales: Iyer, Shama R., Shah, Sameer B., Valencia, Ana P., Schneider, Martin F., Hernández-Ochoa, Erick O., Stains, Joseph P., Blemker, Silvia S., Lovering, Richard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401960/
https://ncbi.nlm.nih.gov/pubmed/27979987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00857.2016
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