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Suite of clinically relevant functional assays to address therapeutic efficacy and disease mechanism in the dystrophic mdx mouse
Duchenne muscular dystrophy (DMD) is a progressive primary myodegenerative disease caused by a genetic deficiency of the 427-kDa cytoskeletal protein dystrophin. Despite its single-gene etiology, DMD’s complex pathogenesis remains poorly understood, complicating the extrapolation from results of pre...
Guardat en:
Publicat a: | J Appl Physiol (1985) |
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Autors principals: | , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Physiological Society
2017
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5401958/ https://ncbi.nlm.nih.gov/pubmed/27932677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00776.2016 |
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