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Decrease in Prosaposin in the Dystrophic mdx Mouse Brain
BACKGROUND: Duchenne muscular dystrophy caused by a mutation in the X-linked dystrophin gene induces metabolic and structural disorders in the brain. A lack of dystrophin in brain structures is involved in impaired cognitive function. Prosaposin (PS), a neurotrophic factor, is abundant in the choroi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828254/ https://ncbi.nlm.nih.gov/pubmed/24244600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080032 |
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