A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection

Coxiella burnetii, the causative agent of Q fever, establishes a unique lysosome-derived intracellular niche termed the Coxiella-containing vacuole (CCV). The Dot/Icm-type IVB secretion system is essential for the biogenesis of the CCV and the intracellular replication of Coxiella. Effector proteins...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Fielden, Laura F., Moffatt, Jennifer H., Kang, Yilin, Baker, Michael J., Khoo, Chen Ai, Roy, Craig R., Stojanovski, Diana, Newton, Hayley J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400844/
https://ncbi.nlm.nih.gov/pubmed/28242621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01046-16
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