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The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells
During immune responses, naïve T cells transition from small quiescent cells to rapidly cycling cells. We have found that T cells lacking TAX1BP1 exhibit delays in growth of cell size and cell cycling. TAX1BP1-deficient T cells exited G(0) but stalled in S phase, due to both bioenergetic and biosynt...
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| Wydane w: | Immunity |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400745/ https://ncbi.nlm.nih.gov/pubmed/28314591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.02.018 |
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