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Controlling multi-cycle replication of live-attenuated HIV-1 using an unnatural genetic switch

A safe and effective human immunodeficiency virus type 1 (HIV-1) vaccine is urgently needed, but remains elusive. While HIV-1 live-attenuated vaccine can provide potent protection as demonstrated in rhesus macaque-simian immunodeficiency virus model, the potential pathogenic consequences associated...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Yuan, Zhe, Wang, Nanxi, Kang, Guobin, Niu, Wei, Li, Qingsheng, Guo, Jiantao
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400733/
https://ncbi.nlm.nih.gov/pubmed/28106981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.6b00373
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