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Construction of a Live-Attenuated HIV-1 Vaccine through Genetic Code Expansion

A safe and effective vaccine against human immunodeficiency virus type 1 (HIV-1) is urgently needed to combat the worldwide AIDS pandemic, but still remains elusive. The fact that uncontrolled replication of an attenuated vaccine can lead to regaining of its virulence creates safety concerns preclud...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Wang, Nanxi, Li, Yue, Niu, Wei, Sun, Ming, Cerny, Ronald, Li, Qingsheng, Guo, Jiantao
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984542/
https://ncbi.nlm.nih.gov/pubmed/24715496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201402092
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