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Construction of a Live-Attenuated HIV-1 Vaccine through Genetic Code Expansion

A safe and effective vaccine against human immunodeficiency virus type 1 (HIV-1) is urgently needed to combat the worldwide AIDS pandemic, but still remains elusive. The fact that uncontrolled replication of an attenuated vaccine can lead to regaining of its virulence creates safety concerns preclud...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Main Authors: Wang, Nanxi, Li, Yue, Niu, Wei, Sun, Ming, Cerny, Ronald, Li, Qingsheng, Guo, Jiantao
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984542/
https://ncbi.nlm.nih.gov/pubmed/24715496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201402092
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