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Systematic Evolution and Study of UAGN Decoding tRNAs in a Genomically Recoded Bacteria

We report the first systematic evolution and study of tRNA variants that are able to read a set of UAGN (N = A, G, U, C) codons in a genomically recoded E. coli strain that lacks any endogenous in-frame UAGN sequences and release factor 1. Through randomizing bases in anticodon stem-loop followed by...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Wang, Nanxi, Shang, Xin, Cerny, Ronald, Niu, Wei, Guo, Jiantao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764823/
https://ncbi.nlm.nih.gov/pubmed/26906548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21898
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