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Amyloid-beta deposition is associated with increased medial temporal lobe activation during memory encoding in the cognitively normal elderly

BACKGROUND: Much is unknown about changes that occur in the brain in the years preceding the cognitive and functional impairment associated with Alzheimer’s disease (AD). This period before mild cognitive impairment is present has been referred to as preclinical AD, and is thought to begin with amyl...

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Détails bibliographiques
Publié dans:Am J Geriatr Psychiatry
Auteurs principaux: Edelman, Kathryn, Tudorascu, Dana, Agudelo, Christian, Snitz, Beth, Karim, Helmet, Cohen, Ann, Mathis, Chester, Price, Julie, Weissfeld, Lisa, Klunk, William, Aizenstein, Howard
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400712/
https://ncbi.nlm.nih.gov/pubmed/28161156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2016.12.021
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