Amyloid-beta deposition is associated with increased medial temporal lobe activation during memory encoding in the cognitively normal elderly

BACKGROUND: Much is unknown about changes that occur in the brain in the years preceding the cognitive and functional impairment associated with Alzheimer’s disease (AD). This period before mild cognitive impairment is present has been referred to as preclinical AD, and is thought to begin with amyl...

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Published in:Am J Geriatr Psychiatry
Main Authors: Edelman, Kathryn, Tudorascu, Dana, Agudelo, Christian, Snitz, Beth, Karim, Helmet, Cohen, Ann, Mathis, Chester, Price, Julie, Weissfeld, Lisa, Klunk, William, Aizenstein, Howard
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400712/
https://ncbi.nlm.nih.gov/pubmed/28161156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2016.12.021
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