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Amyloid-beta deposition is associated with increased medial temporal lobe activation during memory encoding in the cognitively normal elderly

BACKGROUND: Much is unknown about changes that occur in the brain in the years preceding the cognitive and functional impairment associated with Alzheimer’s disease (AD). This period before mild cognitive impairment is present has been referred to as preclinical AD, and is thought to begin with amyl...

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Detalhes bibliográficos
Publicado no:Am J Geriatr Psychiatry
Main Authors: Edelman, Kathryn, Tudorascu, Dana, Agudelo, Christian, Snitz, Beth, Karim, Helmet, Cohen, Ann, Mathis, Chester, Price, Julie, Weissfeld, Lisa, Klunk, William, Aizenstein, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400712/
https://ncbi.nlm.nih.gov/pubmed/28161156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2016.12.021
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