Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

Tetraspanin 8 (TSPAN8) overexpression is correlated with poor prognosis in human colorectal cancer (CRC). A murine mAb Ts29.2 specific for human TSPAN8 provided significant efficiency for immunotherapy in CRC pre-clinical models. We therefore evaluate the feasability of targeting TSPAN8 in CRC with...

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Publicado en:Oncotarget
Autores principales: Maisonial-Besset, Aurelie, Witkowski, Tiffany, Navarro-Teulon, Isabelle, Berthier-Vergnes, Odile, Fois, Giovanna, Zhu, Yingying, Besse, Sophie, Bawa, Olivia, Briat, Arnaud, Quintana, Mercedes, Pichard, Alexandre, Bonnet, Mathilde, Rubinstein, Eric, Pouget, Jean-Pierre, Opolon, Paule, Maigne, Lydia, Miot-Noirault, Elisabeth, Chezal, Jean-Michel, Boucheix, Claude, Degoul, Françoise
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400644/
https://ncbi.nlm.nih.gov/pubmed/28423546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15787
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