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TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life

ADAM10 is a transmembrane metalloprotease that is essential for development and tissue homeostasis. It cleaves the ectodomain of many proteins, including amyloid precursor protein, and plays an essential role in Notch signaling. ADAM10 associates with six members of the tetraspanin superfamily refer...

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Détails bibliographiques
Publié dans:Life Sci Alliance
Auteurs principaux: Eschenbrenner, Etienne, Jouannet, Stéphanie, Clay, Denis, Chaker, Joëlle, Boucheix, Claude, Brou, Christel, Tomlinson, Michael G, Charrin, Stéphanie, Rubinstein, Eric
Format: Artigo
Langue:Inglês
Publié: Life Science Alliance LLC 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892437/
https://ncbi.nlm.nih.gov/pubmed/31792032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900444
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