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Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

Recent reports have confirmed highest levels of growth hormone (GH) receptor (GHR) transcripts in melanoma, one of the most aggressive forms of human cancer. Yet the mechanism of GH action in melanoma remains mostly unknown. Here, using human malignant melanoma cells, we examined the effects of GH e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Basu, Reetobrata, Wu, Shiyong, Kopchick, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400608/
https://ncbi.nlm.nih.gov/pubmed/28223541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15375
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