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Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

Recent reports have confirmed highest levels of growth hormone (GH) receptor (GHR) transcripts in melanoma, one of the most aggressive forms of human cancer. Yet the mechanism of GH action in melanoma remains mostly unknown. Here, using human malignant melanoma cells, we examined the effects of GH e...

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Опубликовано в: :Oncotarget
Главные авторы: Basu, Reetobrata, Wu, Shiyong, Kopchick, John J.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400608/
https://ncbi.nlm.nih.gov/pubmed/28223541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15375
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