Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma

Ipilimumab has revolutionized malignant melanoma therapy, but a better understanding of the mechanisms behind treatment response and adverse effects is needed. In this work, the immune system of ipilimumab treated patients was monitored to investigate potential mechanisms of action that may correlat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: de Coaña, Yago Pico, Wolodarski, Maria, Poschke, Isabel, Yoshimoto, Yuya, Yang, Yuan, Nyström, Maria, Edbäck, Ulrika, Brage, Suzanne Eghyazi, Lundqvist, Andreas, Masucci, Giuseppe V., Hansson, Johan, Kiessling, Rolf
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400604/
https://ncbi.nlm.nih.gov/pubmed/28423487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15368
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