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High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma

The efficacy of immunotherapies for malignant melanoma is severely hampered by local and systemic immunosuppression mediated by myeloid-derived suppressor cells (MDSC). Inhibitor of differentiation 1 (ID1) is a transcriptional regulator that was shown to be centrally involved in the induction of imm...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Melief, Jeroen, Pico de Coaña, Yago, Maas, Roeltje, Fennemann, Felix-Lennart, Wolodarski, Maria, Hansson, Johan, Kiessling, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113206/
https://ncbi.nlm.nih.gov/pubmed/31953577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02476-9
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