Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma

Ipilimumab has revolutionized malignant melanoma therapy, but a better understanding of the mechanisms behind treatment response and adverse effects is needed. In this work, the immune system of ipilimumab treated patients was monitored to investigate potential mechanisms of action that may correlat...

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Vydáno v:Oncotarget
Hlavní autoři: de Coaña, Yago Pico, Wolodarski, Maria, Poschke, Isabel, Yoshimoto, Yuya, Yang, Yuan, Nyström, Maria, Edbäck, Ulrika, Brage, Suzanne Eghyazi, Lundqvist, Andreas, Masucci, Giuseppe V., Hansson, Johan, Kiessling, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400604/
https://ncbi.nlm.nih.gov/pubmed/28423487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15368
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