microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma

Previous studies showed that five miRNAs (miR-885-5p, miR-1274, miR-210-3p, miR-224 and miR-1290) were upregulated the most in clear cell renal cell carcinoma (ccRCC). Our focus was to understand from a clinical standpoint the functional consequences of upregulating miR-210-3p. Towards this, we util...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yoshino, Hirofumi, Yonemori, Masaya, Miyamoto, Kazutaka, Tatarano, Syuichi, Kofuji, Satoshi, Nohata, Nijiro, Nakagawa, Masayuki, Enokida, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400553/
https://ncbi.nlm.nih.gov/pubmed/28152509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14930
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